Health Canada is advising Canadians that natural health products containing the ingredient glucomannan in tablet, capsule or powder form, which are currently on the Canadian market, have a potential for harm if taken without at least 8 ounces of water or other fluid. The risk to Canadians includes choking and/or blockage of the throat, esophagus or intestine, according to international adverse reaction case reports. It is also important to note that these products should NOT be taken immediately before going to bed. Health Canada has authorized some products containing glucomannan for the purposes of appetite reduction, weight management, treatment of constipation, management of cholesterol levels.